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well, this post may not be very helpful for people outside Switzerland or Germany, so the english version of this letter here for our friends outside german-speaking countries: URGENT Field Safety Notice GEHC Ref # 90200 To: Head of Sourcing Head of Quality RE: PAA Laboratories Fetal Bovine Serum (FBS) 3‐21 100ml and 500ml, Quantum 3‐21 100ml and 500ml for in vitro diagnostic applications; Mislabeled. GE Healthcare has become aware of potential product label non‐conformances with the affected PAA Laboratories Fetal Bovine Serum (FBS) products listed below. Please ensure that all potential users in your facility are made aware of this notification and that the instructions below are followed. Safety Issues (1) The FBS products, as listed below, described as ‘specialty sera,’ may contain adult Bovine Serum Albumin (BSA) of United States origin, water, and/or cell growth promoting additives. (2) For FBS product shipped into countries other than the United States, current product labeling for the products listed below states that the origin of the product is either Australia or EU approved serum sources. In addition to, or instead of product of this origin, the product may contain adult BSA of United States origin and/or may contain Fetal Bovine Serum (FBS) from sources including the United States, Canada, Argentina, Brazil, and/or Mexico. Safety Instructions Stop using the product and take the actions described in the product correction section below. Affected Product Details Product Code Product Name Treatment A15‐110 500 ml Fetal Bovine Serum 3‐21 Amnion cell tested A21‐110 100 ml Fetal Bovine Serum 3‐21 Amnion cell tested U11‐020 100 ml Quantum 3‐21 CE‐certified, Medium for Amnion and Chorionic Villi Cells U15‐020 500 ml Quantum 3‐21 CE‐certified, Medium for Amnion and Chorionic Villi Cells U11‐022 100 ml Quantum BPL The cultivation and growth of human lymphocytes for in vitro diagnostic purposes U15‐022 500 ml Quantum BPL The cultivation and growth of human lymphocytes for in vitro diagnostic purposes Page 2 of 2 Product Correction Return any unused product and request reimbursement. Contact your local customer service representative for instructions on how to return the product to us. Contact Information [Insert Local Customer Service Contact] [Insert Local Commercial Contact] Please be assured that maintaining a high level of safety and quality is our highest priority. If you have any questions, please contact us immediately per the contact information above. GE Healthcare confirms that this notice has been notified to the appropriate Regulatory Agency. Sincerely, Nigel Darby Sue Rogers Vice President, BioProcessing Executive, Quality Assurance GE Healthcare Life Sciences & Regulatory Affairs GE Healthcare Life Sciences

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